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What is Fioricet?

Fioricet is a medication composed of acetaminophen, butalbital, and caffeine. Acetaminophen alleviates headache pain, while butalbital, a barbiturate, reduces anxiety and induces relaxation and sleepiness. Caffeine amplifies the effects of acetaminophen by stimulating the central nervous system and reducing blood vessel muscle spasms. This results in an improvement in blood flow.

Fioricet is primarily used to treat tension headaches caused by muscle contractions. It is not available for purchase over-the-counter; it is a prescription medication.
However, it is available for online purchase with a prescription.

Uses of Fioricet

Fioricet is used to treat tension headaches caused by muscle contractions and is also effective for migraines, fever, and pain when used in combination with other medications.

Acetaminophen: Relieves pain and reduces fever.

Butalbital: Acts as a sedative by stimulating the brain’s production of Gamma-Aminobutyric Acid (GABA), a neurotransmitter that calms the nervous system by blocking signals among neurons.

Caffeine: Raises blood pressure, causing blood vessels to constrict and increase blood flow, thereby relieving headaches.

Types of Fioricet

Fioricet is available in pill, tablet, and liquid solution forms, with varying strengths:

Tablet

  • butalbital/acetaminophen/caffeine
  • 50mg/325mg/40mg (Fioricet, Esgic)
  • 50mg/500mg/40mg (Esgic-Plus)
  • 50mg/750mg/40mg (Dolgic Plus)

Capsule

  • butalbital/acetaminophen/caffeine
  • 50mg/300mg/40mg (Orbivan)
  • 50mg/325mg/40mg (Esgic, Margesic)
  • 50mg/500mg/40mg (Esgic-Plus, Zebutal)

Liquid

  • butalbital/acetaminophen/caffeine
  • (50mg/325mg/40mg)15mL (Alagesic LQ)

How to Use Fioricet

Age, health status, and treatment response all affect dosage. Fioricet can be taken by mouth with or without food, as prescribed by a doctor. Take it with food if it upsets your stomach. Overuse can lead to overdose symptoms like nausea, vomiting, loss of appetite, stomach pain, irregular heartbeat, restlessness, tremors, fainting, sweating, confusion, and weakness.

Do not stop taking Fioricet abruptly, as it can cause withdrawal symptoms, especially in individuals who have used it long-term or in high doses. Withdrawal symptoms include mood changes, nausea, vomiting, and seizures. Avoid using this drug in high amounts or for extended periods due to the risk of physical dependence.

Dosage for Tension Headaches

Adult dosage: One or two pills every four hours, as needed, is the standard dosage for adults and children twelve years of age and up. This medication should not be used more than six tablets daily.

Precautions Before Taking Fioricet

Before taking Fioricet, inform your doctor if you are allergic to acetaminophen, caffeine, butalbital, or other barbiturates like phenobarbital, or xanthine derivatives. Also, disclose if you have had:

  • Severe breathing problems (e.g., sleep apnea, asthma)
  • Porphyria (enzyme disorder)
  • Liver or kidney disease
  • Mood disorders
  • Stomach problems
  • History of drug or alcohol addiction
  • History of skin rash from medication

Fioricet can cause dizziness or drowsiness. Avoid alcohol, driving, or operating machinery until you know how the medication affects you. Inform your doctor about all products you use before any surgery or medical procedure. Elderly individuals may be more sensitive to Fioricet’s side effects.

Avoid using Fioricet if you have taken an MAO inhibitor in the past 14 days due to the risk of dangerous drug interactions. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Fioricet may reduce the effectiveness of hormonal birth control methods, potentially leading to pregnancy. Consult your doctor about using other reliable birth control methods while on this medication. Excessive or prolonged use of Fioricet can damage your liver.

Do not use Fioricet during pregnancy as it may harm the unborn child, and high doses or long-term use may cause withdrawal symptoms in newborns (e.g., irritability, vomiting, abnormal crying, seizures, diarrhea). Avoid breastfeeding while taking Fioricet as it passes into breast milk and may affect the baby.

Side Effects of Fioricet

Common side effects include:

  • Dizziness
  • Drowsiness
  • Sleep problems
  • Nausea
  • Vomiting
  • Abdominal pain
  • Constipation
  • Dry mouth
  • Tremor
  • Shortness of breath
  • Lightheadedness
  • Increased urination
  • Weight loss
  • Loss of appetite
  • Jaundice
  • Headache
  • Feeling intoxicated
  • Anxiety

Rarely, acetaminophen can cause severe skin reactions that may be fatal. Symptoms of an allergic reaction include rash, itching or swelling, severe dizziness, and trouble breathing. Discontinue use if such reactions occur.